- The country ratified the Cartagena Protocol in January 2006.
- The competent national authority is Swaziland Environment Authority.
- A Biosafety Act exists since 2012 but is being revised to make it more workable.
- NEPAD Agency ABNE has organized a series of biosafety training workshops for Swaziland stakeholders and regulators in Ezulwini since 2015.
- Cotton: CFT/MLT of Bt cotton approved